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About
Samsung Biologics
America -
Samsung Biologics America is our U.S. subsidiary committed to providing trusted services in close proximity to our clients and industry partners. The San Francisco R&D Center is our first U.S. location, which supports our CDO services.
Service & Facility
The San Francisco R&D Center uses industry-standard equipment, including Cytena Single Cell Printer and Solentim Cell Metric, to perform Cell Line Development (CLD) as fast as 14 weeks (or 3.5 months). Samsung Biologics offers its own proprietary cell line development technology S-CHOice, which builds on glutamine synthase (GS) knock-out Chinese hamster ovary (CHO) cell line technology and shows improved titers up to two-fold from the industry average, reaching above 7 g/L for standard monoclonal antibodies. Our high expression cell line maintains viability over 90% at day-21 in a fed-batch study, demonstrating effectiveness in producing high quality cell lines.
- Transfect CHO GS KO host with vector
- Stable pool generation & selection of high-producing pools ~7 weeks
- Single cell cloning ~ 3 weeks
- Stable clone generation and RCB selection ~ 4 weeks
Directions to
San Francisco R&D Center
600 Gateway Blvd., South San Francisco CA 94080 / +1-650-898-9717
